Most human deaths follow a bite from an infected dog. Rao md 1 slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Rhabdovirus definition is any of a family rhabdoviridae of rod or bulletshaped singlestranded rna viruses found in plants and animals and including the causative agents of rabies and vesicular stomatitis. A novel rhabdovirus associated with acute hemorrhagic fever in. Pada membran selubung amplop terdapat kandungan lemak yang tinggi. The vesicular stomatitis virus is a member of the rhabdovirus family. Genomics and structurefunction studies of rhabdoviridae proteins. A novel rhabdovirus associated with acute hemorrhagic. Albert joubert 7 fish novirhabdoviruses 89 gael kurath 8 the sigma viruses of drosophila 117 ben longdon, lena wilfert and francis m. If so, share your ppt presentation slides online with. Rhabdovirus single stranded,linear,negative sense,non segmented rna these are enveloped bullet shaped virus multiply in cytoplasm 2.
Complete study demonstrating the absence of rhabdovirus in a. Antibodies directed against svcv crossreact to various degrees with other fish rhabdoviruses. Virus tersusun dari ribonukleokapsid dibagian tengah, memiliki membrane selubung amplop dibagian luarnya yang pada permukaannya terdapat tonjoloan spikes yang jumlahnya lebih dari 500 buah. Ma h1, galvin ta1, glasner dr1, shaheduzzaman s1, khan as2. We performed an extensive analysis of our sf9 cell bank atcc crl1711 lot 5814 sf9l5814 to determine whether this virus was already present in cells obtained from atcc in 1987. Ppt rabies powerpoint presentation free to download. Rabies virus family rhabdoviridae jack lam atsuko hilliard roger salinas what is rabies. Rhabdoviruses contains a detailed table of more than 100 taxonomically unassigned viruses, of which more than 90% are unassigned animal rhabdoviruses mostly isolated from arthropods.
The family rhabdoviridae is ecologically diverse and includes viruses that infect a. Moreover, members of the genus have been observed in andor isolated from vertebrate, invertebrate and plant tissues, since the first report of the international committee on nomenclature of viruses icnv in 1971, in. The two plant rhabdovirus genera, nucleorhabdovirus and cytorhabdovirus, can be distinguished on the basis of their intracellular site of morphogenesis in plant cells. There is no evidence to suggest that an apparently healthy blood donor can transmit rabies, even if incubating clinical rabies. About 95% of human deaths occur in asia and africa. The evolutionary challenge faced by rna viruses is to maximize functional diversity within severe constraints on genome size. The rhabdoviridae represent one of the oldest and most feared viral families to plague humankind. Enveloped, bulletshaped, 45100 nm in diameter, 100430 nm in length nucleic acid. Rhabdovirus has become recognized as the generic term for those viruses which exhibit a bulletshaped or bacilliform morphology wildy, 1971. Rabies virus is an enveloped, singlestranded rna virus with bullet shaped or rodshaped morphology. Most virologists and microbiologists have heard of rabies virus, but few will fully appreciate the full scope of the viruses classified into the six genera of the rhabdoviridae family. Singlestranded, linear, negativesense rna genome, 11. With the rural farm towns surrounding small cities like northampton all swinging 100% blue, where one would normally expect them to be red.
After inoculation, rabies virus may enter the peripheral nervous system directly and migrates to the brain or may replicate in muscle tissue, remaining sequestered at or near the entry site during incubation, prior to central nervous system invasion and replication. It is a zoonotic virus and is transmissible to humans from the vesicular fluids and tissues of infected animals. Plant rhabdoviruses are transmitted by aphid, leafhopper or planthopper vectors, and the viruses replicate in both their insect and plant hosts. The family rhabdoviridae are negatively stranded rna viruses consisting of two genera that infect animals lyssavirus and vesiculovirus and the plant rhabdovirus group. Rhabdoviridae is a family of viruses whose members infect vertebrates, invertebrates, and plants see jackson et al. Rabies atau penyakitanjing gila merupakan penyakit mematikan yang disebabkan oleh virus rhabdovirus yang menyerang sistem saraf pusat ssp hewan mamalia termasuk manusia. Food and drug administration fda science board subcommittee. Links to pubmed are also available for selected references. On the basis of rhabdovirus phylogeny and the broad host ranges of rhabdoviruses, we propose that insects are the primary determinants of the rhabdovirus plant and animal host range. The virus ability to gain access to aquaculture farms has also positioned it as a disease of utmost priority once detected in these settings. Susceptible to disinfectants inactivated by drying electron micrograph of rabies. Consists of wound care, rabies immune globulin, and vaccine. Bs,microbiology 5 structure of the rabies virus 5 insert figure 25. In the case of the fish vesiculovirus spring viremia of carp virus svcv there is a single serotype.
Rhabdoviridae a family of arborviruses carried by arthropods arborvirus, arbovirus a large heterogeneous group of rna viruses divisible into. Rhabdoviridae synonyms, rhabdoviridae pronunciation, rhabdoviridae translation, english dictionary definition of rhabdoviridae. Outbreak of hirame rhabdovirus infection in cultured spotted sea bass lateolabrax maculatus on the western coast of korea article pdf available in journal of fish diseases 3910 june 2016. There has never been a reported case of rabies infec tion via a blood transfusion. All plant rhabdoviruses carry analogs of the five core genes. It affects humans as well as domestic and wild animals.
Ppt rhabdoviridae powerpoint presentation free to download id. Identification of a novel rhabdovirus in spodoptera. A free powerpoint ppt presentation displayed as a flash slide show on id. Choose from 60 different sets of rhabdovirus flashcards on quizlet. Identification of a novel rhabdovirus in spodoptera frugiperda cell lines. It then spreads centrifugally to numerous other organs. Virus is associated with the buffy coat fraction of the blood. In the present study, we engineered an attenuated maraba strain, defined as mg1, to. Rhabdovirus family rhabdoviridae has a single negativestrand rna genome. Rabies widely spread in asia and africa rabies is widely distributed across the globe. There is no practical way to prevent occupational exposure. Rhabdoviridae definition of rhabdoviridae by medical dictionary. Remove this presentation flag as inappropriate i dont like this i like this remember as a favorite.
Food and drug administration, bethesda, maryland, usa. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. Rhabdovirus, lyssavirus genus the family rhabdoviridae consists of more than 185 different viruses isolated from both plants and animals. Arthropodborne rhabdoviruses of ruminants, with large, complex genomes 59 peter j. The rhabdovirus maraba has recently been characterized as a potent oncolytic virus. Rhabdovirus free download as powerpoint presentation. Learn rhabdovirus with free interactive flashcards. Pdf maraba virus as a potent oncolytic vaccine vector. For example, if a transcription finishes at the end of m sequence. The rhabdoviridae family is comprised of over 150 viruses of vertebrates, invertebrates and plants. The adobe flash plugin is needed to view this content. Here we show that rhabdoviruses, a family of rna viruses that infect hosts as diverse as plants, insects and. Rhabdoviridae proteins involved in replication and transcription. Scribd is the worlds largest social reading and publishing site.
If you continue browsing the site, you agree to the use of cookies on this website. Rhabdovirus single stranded,linear,negative sense,non segmented. Rabies ppt by dr sujith chadala slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. The rhabdoviruses are approximately 70 nm wide and 170 nm long. Rhabdoviruses study guide by ccmusgrove includes 18 questions covering vocabulary, terms and more. This family of viruses also comprises the genera novirhabdovirus, which exclusively infects fish.
Pdf outbreak of hirame rhabdovirus infection in cultured. Rabies is a viral infection that mainly spreads through a bite from an infected animal. Author summary understanding the patterns and mechanisms of genome evolution is one of the most important, yet least understood, aspects of rna virus biology. Rhabdovirus 0 points 1 point 2 points 3 years ago i think western mass is an interesting case. Most and perhaps all plant rhabdoviruses are rounded at both ends to give a bacilliform shape. Get a printable copy pdf file of the complete article 5. Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that. The bullets surrounding the smooth gray circle are rabies. Rhabdoviridae international committee on taxonomy of. Here, we focus on vesicular stomatitis virus vsv, a prototype of animal rhabdovirus. A simple alphabetical classification is offered as a means to codify the proteins of rhabdoviruses, using vesicular stomatitis virus as the prototype.
Viremia has not been demonstrated, and the virus is intraneuronal during the incubation period. Full text get a printable copy pdf file of the complete article 444k, or click on a page image below to browse page by page. Pdf rabies is an incurable albeit preventable disease that remains an important human health issue. Schneider general rabies info rabies is a violently deadly animal disease spreads as a virus through animals such as. Rabies is the most notable human disease that is caused by this family of viruses. Single stranded,linear,negative sense,non segmented rna. The family rhabdoviridae consists of more than 100 singlestranded, negativesense, nonsegmented viruses that infect a wide variety of hosts, including. However, while ive been looking for a group, ive noticed that most people are outside what i as an outsider consider cincinnati proper. Importantly there is no definitive clinical presentation for rabies and in all. The family rhabdoviridae consists of more than 100 singlestranded, negative sense, nonsegmented viruses that infect a wide variety of hosts, including. Most contributions are written from a molecular and genomic perspective and contain expert insights upon which to base future research efforts. Here we show that rhabdoviruses, a family of rna viruses that infect hosts as diverse as.
A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. These specific interactions between plants, viruses and insects offer new insights into host adaptation and molecular virus evolution. A putative novel rhabdovirus sfrv was previously identified in a spodoptera frugiperda cell line sf9 cells atcc crl1711 lot 58078522 by next generation sequencing and extensive bioinformatic analysis. Pathogenesis enters the body through breaks in the mucosa. Evolution of genome size and complexity in the rhabdoviridae.
Identification of a novel rhabdovirus in spodoptera frugiperda cell. Pdf structure, interactions with host cell and functions of. Virus berukuran panjang 180 nm, diameter 75 nm, tonjolan berukuran 9 nm, dan jarak antara spikes 4. Rabies virus structure and pathogenesis microbeonline. Presentations ppt, key, pdf logging in or signing up. The rhabdovirus ranscriptase proceeds in a 3 to 5 direction on the genome and the transcription terminates randomly at the end of protein sequences. Plant rhabdoviruses are transmitted by and replicate in hemipteran insects such as aphids aphididae, leafhoppers cicadellidae, or planthoppers delphacidae. The virus, a rhabdovirus, is often present in the salivary glands of rabid animals and is excreted in the saliva. Winner of the standing ovation award for best powerpoint templates from presentations magazine. Early rabies it has been recognized in india since the vedic period 1500500 bc and is described in the ancient indian scripture atharvaveda, rabies is endemic in india, a vast country with a population exceeding 1. Rabies ppt free download as powerpoint presentation. Between 30% to 60% of the victims of dog bites are children under the age of 15. Quizlet flashcards, activities and games help you improve your grades. Virions 100430 by 45100 nm, formed by budding from surface membranes of cells, are enveloped and ether sensitive, with surface spikes 510 nm long.
We currently have several openings for writing workers. Rabies is an infectious viral disease caused by rabies virus. Two of the genera within the family, vesiculovirus and lyssavirus, are more familiarly known as the causative agents of vesicular stomatitis and rabies in humans. Rhabdovirus definition of rhabdovirus by merriamwebster. Full text full text is available as a scanned copy of the original print version. The difficulty of assigning an official taxonomy is explained. Jiggins 9 virushost protein interactions of plantadapted rhabdoviruses 3.
In general, vhsv causes severe degeneration in the hematopoietic tissues of affected fish. Rabies virus, epidemiology, transmission and freeroaming cats. Rhabdoviruses is the property of its rightful owner. Rabies virus, epidemiology, transmission and freeroaming. They first transcribe a positive rna template, then use that template to regenerate their negative rna genome. We used deep sequencing, a method for generating millions of dna sequence reads from clinical samples, to discover a novel rhabdovirus bascongo virus, or basv associated with a 2009 outbreak of 3 human cases of acute hemorrhagic fever in mangala village, democratic republic of congo drc, africa.
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